The Laboratory of Protein Expression and Cell Engineering operates as a research and development lab as well as a core facility within the Center for Clinical Genomics and Personalised Medicine (currently renamed to Genome Medicine and Bioinformatics Core Facility), Department of Biochemistry and Molecular Biology at the Faculty of General Medicine, University of Debrecen.As a development laboratory, we are working on proprietary technologies and biotech products in the field of protein expression, monoclonal antibodies, recombinant proteins, cell engineering, functional genomics and epigenetics. As a core facility, we provide advanced protein expression services using optimised synthetic genes and a wide range of host organisms (bacterial, yeast, insect, mammalian) for small and large scale protein production, and equipped for state-of –the-art protein purification and biochemical/biological characterisation – a full Gene-to-Protein service .
Also, we are routinely developing single and multiple transgenic or knockout stable mammalian cell lines using cell/genome engineering technologies for research, bioassay, recombinant protein production, or any custom applications to your needs. The laboratory is also offering custom monoclonal antibody development starting from antigen sequence, through epitope design up to small or large scale purified antibody preparations. We have a custom recombinant cytokine development workflow and offer cytokine expressing stable cell lines or purified cytokines. We are ready to help you with our consultation services for project and method development and special services in the field of protein engineering, directed molecular evolution, phage display technology and high throughput screening. Our services are fast and quality controlled internally with the potential for external QA in the near future. Please, consult Dr. Zsolt Keresztessy, Head of PROXENCELL Laboratory for detailed information on collaborative research and development potentials, services/products. (Director of the Genomics Unit is Prof. Dr. László Nagy, who is currently a Program Director at Samford-Burnham MRI)

The Laboratory Establishment Project was sponsored by MAG Zrt. - Hungarian Economic Development Center, North-Great Plain Region Gábor Baross Program, REG_EA_KFI_09-INNANTet. PLEASE, SEE REFERENCES FOR MORE INFORMATION.